Methacrylated Hyaluronan and Poly(vinyl alcohol) Scaffolds for Periodontal Tissue Regeneration

Preparation and Characterization of Aligned and Random Nanofibrous Nanocomposite Scaffolds of Poly (Vinyl Alcohol), Poly (e-Caprolactone) and Nanohydroxyapatite

Nanofibrous scaffolds produced by electrospinning have attracted much attention, recently. Aligned and random nanofibrous scaffolds of poly (vinyl alcohol) (PVA), poly (ε-caprolactone) (PCL) and nanohydroxyapatite  (nHA) were fabricated by electrospinning method in this study. The composite nanofibrous scaffolds were subjected to detailed analysis. Morphological investigations revealed that the...

Partial Resurfacing of the Distal Femoral Cartilage Defect with Stem Cell- Seeded Poly-Vinyl-Alcohol (PVA) Scaffold

Objective- To evaluate the biological compatibility of differentiated stem cells embedded in poly-vinyl-alcohol (PVA) scaffolds for repair of distal femoral cartilage defect.   Design- Experimental in vivo study. Animals- Twelve adult male New Zealand white rabbits were used which were divided into two groups (I, II) six rabbits each.   Procedures- Mesenchymal stem cells were isolated from h...

Biological Properties of Blend Nanofibrous Scaffolds from Poly(caprolactone)-Chitosan-Poly(vinyl alcohol)

Aligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering

Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...

Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering

In vitro-generated soft tissue could provide alternate therapies for soft tissue defects. The aim of this study was to evaluate methacrylated gelatin/hyaluronan as scaffolds for soft tissue engineering and their interaction with human adipose-derived stem cells (hASCs). ASCs were incorporated into methacrylated gelatin/hyaluronan hydrogels. The gels were photocrosslinked with a lithium phenyl-2...